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#vaccination

6 posts6 participants0 posts today

JAMA:

March 14, 2025
Revising US MMR Vaccine Recommendations Amid Changing Domestic Risks

"...The committee outlines a few special cases for the administration of a third lifetime dose, including during an ongoing measles or mumps outbreak and among high-risk groups (eg, health care workers and immunocompromised individuals). Additionally, for children aged 6 to 11 months scheduled to travel internationally, the committee recommends an additional early dose (ie, a third dose) of the MMR vaccine before travel, administered before initiating their routine 2-dose series at age 12 months. Historically, disease importations from unvaccinated children traveling internationally to endemic regions has been the major source of US measles cases. However, multiple recent US measles outbreaks, coupled with low vaccination rates, signal a growing domestic hazard..."

jamanetwork.com/journals/jama/

Antivaxxers are a public health problem. Newborn babies risked lifelong maiming because a willfully ignorant adult brought measles into a maternity unit.

#measles #vaccination

“Newborn babies exposed to measles in Texas hospital”

nbcnews.com/health/health-news

NBC News · As Texas measles outbreak grows, newborn babies were exposed to the virus in Lubbock hospitalBy Erika Edwards

Newborn babies have been exposed to measles at a Texas hospital and are receiving antibodies to protect them, NBC reports. The virus was brought into the University Medical Center Children's Hospital by a mother in labor — doctors didn't realize until after her admission that she was infected, and it's unclear when she tested positive. The immunoglobulin injections have been given to babies as young as three days old. A 2021 study found this therapy is highly effective in protecting exposed newborns who are too young to be vaccinated. Emergency masking procedures have also been implemented.

flip.it/0.ZRbx

NBC News · As Texas measles outbreak grows, newborn babies were exposed to the virus in Lubbock hospitalBy Erika Edwards

The mRNA technology behind coronavirus vaccines is now being used to create bespoke vaccines for cancer patients.

"Cancer vaccines weren’t a proper field of research before the pandemic. There was nothing. Apart from one exception, pretty much every clinical trial had failed. With the pandemic, however, we proved that mRNA vaccines were possible.

mRNA cancer vaccines work by giving the body instructions to make a harmless piece of a cancer-related protein. This trains the immune system to recognize and attack cancer cells carrying that protein. Think of it like a training manual for security guards. The vaccine gives the immune system a guide on what cancer looks like, so it knows exactly who to watch for and remove.

Going from mRNA Covid vaccines to mRNA cancer vaccines is straightforward: same fridges, same protocol, same drug, just a different patient.

In the current trials, we do a biopsy of the patient, sequence the tissue, send it to the pharmaceutical company, and they design a personalized vaccine that’s bespoke to that patient’s cancer. That vaccine is not suitable for anyone else. It’s like science fiction.

The UK was ready. We had fridges and we had world-class manufacturing and research facilities. During the pandemic, we had proven we could open and deliver clinical trials fast. Also, the UK had established a genomic global lead with Genomics England and the 100,000 Genome Project. All doctors and nurses in this country are trained in genomics.

So the UK government signed two partnerships: one with BioNTech to provide 10,000 patients with access to personalized cancer treatments by 2030, and a 10-year investment with Moderna in an innovation and technology center with capacity to produce up to 250 million vaccines. The stars were aligned.

For many years, we believed that research is inherently slow. It used to take 20 years to get a drug to market. Most cancer patients, unfortunately, will succumb by the time a drug gets to market. We showed the world that it could be done in a year if you modernize your process, run parts of the process in parallel, and use digital tools.

We have a trial to stop skin cancer coming back after you cut it out. It’s now completed. We over-recruited again, just like every single one of the trials that we ran, and the trial finished one year ahead of schedule. That’s completely unheard of in cancer trials because they normally run over-long.

What will happen now is that, over the next six to 12 months, we will monitor the people in the trial and work out if there’s a difference between the people who took the cancer vaccine and the ones who didn’t. We’re hoping to have results by the end of the year or beginning of 2026. If it’s successful, we will have invented the first approved personalized mRNA vaccine, within only five years of the first licensed mRNA vaccine for Covid. That’s pretty impressive."

- Dr. Lennard Lee, UK National Health Service oncologist and medical director at the Ellison Institute of Technology in Oxford

wired.com/story/wired-health-l

WIRED · Covid Vaccines Have Paved the Way for Cancer VaccinesBy João Medeiros
Continued thread

"...Pharmacies at H-E-B, the grocery chain, in Austin are now limiting MMR vaccines to those most at risk, including people born before 1989 who may have only received one dose...."

(Hey, that was me until yesterday! Whoohoo, ahead of the curve!)

Essais cliniques pour un vaccin intranasal contre le covid, par un groupe français (financé essentiellement sur crédits INSERM)

Ils recherchent des volontaires en bonne santé (pas mal de critères voir : clinicaltrials.gov/study/NCT06)

Lieux :
#Dijon, #Lyon, #Paris, Saint Priest en Jarez (#SaintEtienne), #Tours
Il faut aussi s'engager à prendre des mesures de précaution (masque) pendant l'étude.

un article plus général : absolutelymaybe.plos.org/2025/

#CovidIsNotOver
#Vaccination

Houston Public Media: Texas measles outbreak grows amid declining vaccination rates in Houston area, statewide

""We are, unfortunately, seeing a trend, not just here locally but across the United States of parents, of people, choosing not to be vaccinated"

""Measles is basically the canary in the mine, highlighting that we're vulnerable to these diseases that we thought were well controlled"

houstonpublicmedia.org/article

New round of polio vaccinations begins in Gaza | UN News (2025-02-22)

news.un.org/en/story/2025/02/1
———

“The latest round of a large-scale polio vaccination campaign in Gaza targeting nearly 600,000 young children got underway on Saturday.”

“The campaign is being led by the Palestinian Ministry of Health and implemented with support from the World Health Organization (#WHO), the UN Children’s Fund (#UNICEF), UN Palestine refugee agency #UNRWA and other partners.”

#Polio #vaccination
@palestine@lemmy.ml @palestine@a.gup.pe @israel

UN News · New round of polio vaccinations begins in GazaThe latest round of a large-scale polio vaccination campaign in Gaza targeting nearly 600,000 young children got underway on Saturday.

Roald Dahl’s Heartbreaking Letter About Losing his Daughter to measles in 1962 - Roald Dahl, the beloved author of my personal favorites Charlie and the Chocolate Factory, Matilda and The BFG, lost his eldest daughter, Olivia, to #measles in the early 60s. It wasn’t until 1988, however, that he penned a remarkable letter that doubles as a plea to parents, urging them to have their children vaccinated… #Vaccines #Vaccination #PublicHealth #InfectiousDisease #epidemiology

fs.blog/roald-dahl-letter-daug

Farnam Street · Roald Dahl's Letter About Losing his Daughter in 1962" there is today something that parents can do to make sure that this sort of tragedy does not happen to a child of theirs. "

There's a growing measles outbreak in Texas with most of the cases in children (all unvaccinated or with unknown vaccination status)...

Measles is highly contagious. If one person has it, up to 9 out of 10 people nearby will become infected if they are not protected. You can get measles just by being in a room where a person with measles has been, even up to 2 hours after that person has left.

And from Stephanie Soucheray at CIDRAP at the University of Minnesota

"Clinicians and epidemiologists have long known that measles infection increases childhood morbidity and mortality for as long as 5 years after illness, and measles in the pre-vaccination era was likely associated with at least half of all childhood deaths from infectious diseases."

cidrap.umn.edu/measles/measles

CIDRAPMeasles does long-term damage to immune system, studies show

Flu is starting to spike in Alberta. The vaccine immunity matched the virus well this season, but the vaccine induced defense is degraded after 3 months. I got my vaccine in early Oct (4.5 m ago) so I asked AB Public Health if any remaining doses can be used for boosters. Nope, they will instead chuck them in the garbage if unused.

Replied in thread

@COVID19_DISEASE

Looking on Ground.News for "flu surge", I found the following from three days ago, with 131 sources. There's only 6% coverage on the right, though.

--

Flu season in the US is the most intense it’s been in at least 15 years

ground.news/article/flu-season

Ground News · Flu season in the US is the most intense its been in at least 15 yearsBy Washington Top News